John D Fryer Selected Research

Pharmaceutical Preparations

1/2017

Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice.

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John D Fryer Research Topics

Disease

27	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 03/2003
8	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020 - 12/2006
6	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2017 - 08/2003
5	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2018 - 01/2016
5	Frontotemporal Dementia (Semantic Dementia) 01/2018 - 01/2016
4	Dementia (Dementias) 09/2021 - 01/2017
4	Gliosis 11/2020 - 01/2019
4	Amyloidosis 11/2020 - 10/2004
4	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 11/2011 - 12/2006
4	Amyloid Plaque 10/2011 - 03/2005
3	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 01/2022 - 10/2020
3	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2021 - 01/2018
3	Tauopathies 01/2019 - 01/2018
3	Cognitive Dysfunction 12/2018 - 05/2016
3	Hemorrhage 03/2005 - 08/2003
2	Ataxia (Dyssynergia) 01/2021 - 10/2020
2	Hypercholesterolemia 01/2021 - 10/2004
2	Parkinson Disease (Parkinson's Disease) 01/2020 - 01/2017
2	Lewy Body Disease (Lewy Body Dementia) 01/2020 - 01/2017
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2019 - 10/2018
2	Corticobasal Degeneration 01/2019 - 10/2018
2	Hypoxia (Hypoxemia) 12/2018 - 01/2018
2	Neuroinflammatory Diseases 10/2018 - 01/2017
2	Multiple Sulfatase Deficiency Disease (Mucosulfatidosis) 12/2012 - 08/2012
1	Shock 01/2022
1	Cerebellar Ataxia (Dysmetria) 01/2022
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2021
1	Atherosclerosis 01/2021
1	Synucleinopathies 01/2020
1	Atrophy 01/2019
1	TDP-43 Proteinopathies 01/2019
1	Hypotension (Low Blood Pressure) 12/2018
1	Hyperthermia 12/2018
1	Hyperglycemia 01/2018
1	Hypoglycemia (Reactive Hypoglycemia) 01/2018
1	Xeroderma Pigmentosum (Kaposi's Disease) 01/2016
1	Inflammation (Inflammations) 02/2015
1	Cholestasis 02/2015
1	Obesity 09/2014
1	Neurodevelopmental Disorders 06/2008
1	Rett Syndrome (Rett's Disorder) 06/2008

Drug/Important Bio-Agent (IBA)

15	Amyloid (Amyloid Fibrils)IBA 12/2020 - 08/2003
13	Proteins (Proteins, Gene)FDA Link 10/2020 - 08/2003
12	Apolipoproteins E (ApoE)IBA 01/2022 - 03/2003
8	ApolipoproteinsIBA 01/2021 - 08/2003
7	Peptides (Polypeptides)IBA 11/2020 - 08/2003
6	polyglutamineIBA 01/2022 - 12/2006
5	Amyloid beta-PeptidesIBA 07/2005 - 08/2003
4	Apolipoprotein E3IBA 09/2021 - 03/2005
4	Apolipoprotein E4IBA 01/2021 - 03/2005
4	Ataxin-1IBA 11/2011 - 12/2006
3	ClusterinIBA 01/2021 - 01/2016
3	Apolipoprotein E2IBA 10/2020 - 05/2016
2	Ataxin-3IBA 01/2021 - 10/2020
2	ProgranulinsIBA 10/2020 - 01/2018
2	NucleotidesIBA 01/2019 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 12/2018 - 01/2018
2	RNA (Ribonucleic Acid)IBA 01/2018 - 07/2010
2	CholesterolIBA 05/2016 - 10/2004
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 03/2005 - 09/2003
1	Adenosine Monophosphate (AMP)IBA 01/2021
1	Molecular Chaperones (Chaperone, Molecular)IBA 12/2020
1	Biological ProductsIBA 10/2020
1	lysosomal proteinsIBA 10/2020
1	UbiquitinIBA 10/2020
1	SynucleinsIBA 01/2020
1	Green Fluorescent ProteinsIBA 01/2019
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2019
1	Vancomycin FDA LinkGeneric 12/2018
1	QuinolonesIBA 12/2018
1	Hypnotics and Sedatives (Sedatives)IBA 01/2018
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2018
1	DipeptidesIBA 01/2018
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2018
1	Analgesics (Analgesic Drugs)IBA 01/2018
1	CateninsIBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Presenilin-1IBA 01/2017
1	alpha-SynucleinIBA 01/2017
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 03/2016
1	plexinIBA 01/2016
1	poly(glycyl-alanyl)IBA 01/2016
1	Ubiquitinated ProteinsIBA 01/2016
1	tau Proteins (tau Protein)IBA 11/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2015
1	Biomarkers (Surrogate Marker)IBA 09/2014
1	Lysergic Acid Diethylamide (LSD)IBA 12/2012
1	SulfatasesIBA 08/2012
1	Epidermal Growth Factor (EGF)IBA 11/2011
1	AtaxinsIBA 07/2010
1	Methyl-CpG-Binding Protein 2IBA 06/2008
1	Glutamine (L-Glutamine)FDA Link 03/2007
1	LDL Receptors (LDL Receptor)IBA 07/2005
1	Lipoproteins (Lipoprotein)IBA 10/2004
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 10/2004

Therapy/Procedure

2	Therapeutics 10/2020 - 09/2014
1	Artificial Respiration (Mechanical Ventilation) 01/2018
1	Enteral Nutrition (Feeding, Tube) 01/2018
1	Critical Care (Surgical Intensive Care) 01/2018
1	Extracorporeal Membrane Oxygenation 01/2018